Regenerative Medicine
Text Box: Sepax is the only automated system to offer specific separation protocols for different regenerative medicine applications. Biosafe’s validated protocols are based on different separation methods, such as nucleated cell component (buffy-coat) concentration, a density gradient based separation that depletes both stem blood cells and granulocytes as well as volume reduction of aphaeresis product to retain the buffy-coat. Each protocol is associated with a single-use kit to provide sterile conditions. Density Gradient Based Separation (DGBS) Isolation of highly purified mononuclear cell (MNC) component with high red blood and granulocyte cell depletion by means of a density gradient medium. Generic Volume Reduction (GVR) Protocol for concentration of the buffy-coat fraction, mainly conceived for bone marrow volume reduction. PBSC Protocol for concentration of the buffy-coat fraction from aphaeresis product by plasma depletion. PBSC Washing Protocol for the removal of cryoprotectant solution from thawed PBSC.

Concentrated stem cell

Heart, post myocardial infraction revascularized by PCI + stent

Baloon occlusion → stem cell infusion

Sepax stem cell processing

Bone marrow extraction (50ml)
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Blood Cold Chain

Cell Processing

Hygiene Systems

Reg-med

Sepax

Cell-bank

Sepax system has the capability to offer spectacular solutions in regenerative medicine applications by processing  a variety of cellular products.

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